{"id":141,"date":"2023-11-15T22:40:56","date_gmt":"2023-11-15T13:40:56","guid":{"rendered":"https:\/\/nakano-dm.clinic\/blog\/?p=141"},"modified":"2023-11-15T22:42:53","modified_gmt":"2023-11-15T13:42:53","slug":"post-141","status":"publish","type":"post","link":"https:\/\/nakano-dm.clinic\/blog\/post-141\/","title":{"rendered":"\u65e5\u672c\u3067\u3057\u304b\u4f7f\u7528\u3067\u304d\u306a\u3044\u30c4\u30a4\u30df\u30fc\u30b0\uff08\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff09\u306e\u9b45\u529b"},"content":{"rendered":"\n<p>2023\u5e7411\u670812\u65e5\u304b\u308911\u670818\u65e5\u306f\u7cd6\u5c3f\u75c5\u9031\u9593\u3067\u3059\u3002\u672c\u65e5\u306f\u7cd6\u5c3f\u75c5\u9031\u9593\u3068\u3044\u3046\u3053\u3068\u3082\u3042\u308a\u3001\u524d\u56de\u306b\u5f15\u304d\u7d9a\u304d\u7cd6\u5c3f\u75c5\u306b\u95a2\u9023\u3059\u308b\u30c6\u30fc\u30de\u3067\u304a\u8a71\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3059\u3002\u4eca\u56de\u306f\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u306e\u30c4\u30a4\u30df\u30fc\u30b0\uff08\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff09\u306e\u9b45\u529b\u306b\u3064\u3044\u3066\u304a\u8a71\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"242\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/11_03.jpg\" alt=\"\" class=\"wp-image-142\" style=\"width:308px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/11_03.jpg 500w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/11_03-400x194.jpg 400w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(\u51fa\u5178\uff1a\u6771\u4eac\u90fd)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u73fe\u5728\u3001\u7cd6\u5c3f\u75c5\u306e\u5185\u670d\u85ac\u306f\u5168\u90e8\u30679\u7a2e\u985e\u3042\u308a\u307e\u3059\u304c\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u305d\u306e\u4e2d\u3067\u6700\u3082\u65b0\u3057\u3044\u85ac\u5264\u3067\u30012021\u5e749\u670816\u65e5\u306b\u767a\u58f2\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u3057\u30662023\u5e7411\u6708\u73fe\u5728\u3001\u65e5\u672c\u3067\u306e\u307f\u4f7f\u7528\u3067\u304d\u308b\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u3046\u306a\u308b\u3068\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u30e1\u30a4\u30c9\u30a4\u30f3\u30b8\u30e3\u30d1\u30f3\u306e\u3088\u3046\u306b\u601d\u308f\u308c\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u3053\u308c\u306f\u30d5\u30e9\u30f3\u30b9\u306e\u30dd\u30af\u30bb\u30eb\u793e\u304c\u958b\u767a\u3057\u3001\u65e5\u672c\u306e\u88fd\u85ac\u30e1\u30fc\u30ab\u30fc\u3068\u9023\u643a\u3057\u3066\u81e8\u5e8a\u7814\u7a76\u3092\u884c\u3044\u3001\u88fd\u9020\u8ca9\u58f2\u306b\u3053\u304e\u3064\u3051\u305f\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u3001\u7cd6\u5c3f\u75c5\u306e\u5185\u670d\u85ac\u3067\u3042\u308b\u30e1\u30c8\u30b0\u30eb\u30b3\uff08\u30e1\u30c8\u30db\u30eb\u30df\u30f3\uff09\u306e\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u3067\u3042\u308b\u4e73\u9178\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u3092\u56de\u907f\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u306b\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u4e0b\u56f3\u306b\u793a\u3059\u3088\u3046\u306b\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u30e1\u30c8\u30b0\u30eb\u30b3\u3068\u975e\u5e38\u306b\u985e\u4f3c\u3057\u305f\u69cb\u9020\u3092\u6709\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u985e\u4f3c\u6027\u306b\u3088\u308a\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u30e1\u30c8\u30b0\u30eb\u30b3\u3068\u4e00\u90e8\u3067\u540c\u69d8\u306e\u4f5c\u7528\u3092\u6709\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u540c\u6642\u306b\u30e1\u30c8\u30b0\u30eb\u30b3\u306b\u306f\u898b\u3089\u308c\u306a\u3044\u72ec\u81ea\u306e\u4f5c\u7528\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"434\" height=\"180\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/vol39_no3_264_1.png\" alt=\"\" class=\"wp-image-143\" style=\"width:329px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/vol39_no3_264_1.png 434w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/vol39_no3_264_1-400x166.png 400w\" sizes=\"auto, (max-width: 434px) 100vw, 434px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(\u51fa\u5178\uff1a\u7cd6\u5c3f\u75c5\u30bd\u30fc\u30b9\u30ac\u30a4\u30c9)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u4e3b\u306b4\u3064\u306e\u4f5c\u7528\u304c\u3042\u308a\u3001\u3053\u308c\u306b\u3064\u3044\u3066\u308f\u304b\u308a\u3084\u3059\u304f\u8aac\u660e\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>1\u3064\u76ee\u306f\u3001\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u95a2\u9023\u85ac\uff08DPP-4\u963b\u5bb3\u85ac\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306a\u3069\uff09\u3067\u8a8d\u3081\u3089\u308c\u308b\u3001\u8840\u7cd6\u5024\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u591a\u304f\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5206\u6ccc\u3059\u308b\u52b9\u679c\u3067\u3059\u3002\u30c4\u30a4\u30df\u30fc\u30b0\u304c\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u4f5c\u7528\u3057\u3001\u7d30\u80de\u5185\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3059\u308bNAD+\u3068\u3044\u3046\u88dc\u9175\u7d20\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u4fc3\u9032\u3055\u308c\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25694060\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25694060<\/a>\uff09<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u8840\u7cd6\u5024\u304c\u4f4e\u3044\u6642\u306b\u306f\u3042\u307e\u308a\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u306a\u3044\u305f\u3081\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u5358\u5264\u3067\u6cbb\u7642\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u4f4e\u8840\u7cd6\u306e\u30ea\u30b9\u30af\u304c\u975e\u5e38\u306b\u5c11\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u95a2\u9023\u85ac\u3068\u540c\u69d8\u3001\u98df\u5f8c\u306e\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u3048\u3001\u8840\u7cd6\u5909\u52d5\u3092\u5c11\u306a\u304f\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u4f4e\u8840\u7cd6\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3057\u3001\u8840\u7cd6\u5909\u52d5\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u306f\u3001\u4ee5\u524d\u306e\u30d6\u30ed\u30b0\u300c<a href=\"https:\/\/nakano-dm.clinic\/blog\/post-18\" title=\"\">\u8840\u7cd6\u5909\u52d5\u3068HbA1c\u306b\u3064\u3044\u3066<\/a>\u300d\u3067\u3082\u89e6\u308c\u307e\u3057\u305f\u304c\u3001\u3053\u306e\u3053\u3068\u306f\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u306e\u30ea\u30b9\u30af\u4f4e\u6e1b\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>2\u3064\u76ee\u306f\u3001\u4f53\u5185\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u751f\u6210\u3059\u308b\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u3092\u4fdd\u8b77\u3059\u308b\u4f5c\u7528\u304c\u3042\u308a\u3001\u3053\u308c\u306f\u985e\u4f3c\u85ac\u306e\u30e1\u30c8\u30b0\u30eb\u30b3\u306b\u306f\u306a\u3044\u7279\u6709\u306e\u4f5c\u7528\u3067\u3059\u3002\u30c4\u30a4\u30df\u30fc\u30b0\u304c\u7d30\u80de\u5185\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u4f5c\u7528\u3057\u3001\u6d3b\u6027\u9178\u7d20\u306e\u7523\u751f\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f5c\u308b\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u3092\u5b88\u308b\u306e\u3067\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27551496\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27551496<\/a>\uff09<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u306f\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u306e\u6295\u4e0e\u306b\u3088\u3063\u3066\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u304c\u5897\u52a0\u3057\u305f\u3068\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u7d50\u679c\u304b\u3089\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u304c\u7cd6\u5c3f\u75c5\u3084\u52a0\u9f62\u306b\u4f34\u3046\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u4f4e\u4e0b\u3092\u9632\u304e\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u6cbb\u7642\u304c\u5fc5\u8981\u306a\u4eba\u3092\u6e1b\u3089\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002(<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34588186\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34588186<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>3\u3064\u76ee\u306f\u3001\u7b4b\u8089\u3084\u809d\u81d3\u306a\u3069\u3001\u8840\u7cd6\u3092\u53d6\u308a\u8fbc\u3080\u81d3\u5668\u306b\u304a\u3044\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u52b9\u679c\u3092\u9ad8\u3081\u308b\u52b9\u679c\u3001\u3064\u307e\u308a\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u6539\u5584\u3055\u305b\u307e\u3059\u3002\u3053\u306e\u4f5c\u7528\u306b\u3088\u308a\u3001\u7b4b\u8089\u3084\u809d\u81d3\u306a\u3069\u304c\u7cd6\u3092\u3088\u308a\u52b9\u679c\u7684\u306b\u53d6\u308a\u8fbc\u3080\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u305d\u306e\u7d50\u679c\u3068\u3057\u3066\u8840\u7cd6\u5024\u304c\u4f4e\u4e0b\u3057\u307e\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25552598\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25552598<\/a>\uff09<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>4\u3064\u76ee\u306f\u3001\u985e\u4f3c\u85ac\u306e\u30e1\u30c8\u30b0\u30eb\u30b3\u3067\u3082\u8a8d\u3081\u3089\u308c\u308b\u809d\u81d3\u3067\u306e\u7cd6\u65b0\u751f\uff08\u7cd6\u8cea\u4ee5\u5916\u306e\u7269\u8cea\u304b\u3089\u30b0\u30eb\u30b3\u30fc\u30b9\u3092\u5408\u6210\uff09\u3092\u6291\u3048\u308b\u50cd\u304d\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u4f53\u5185\u3067\u306e\u7cd6\u306e\u751f\u6210\u304c\u6e1b\u5c11\u3057\u3001\u8840\u7cd6\u5024\u304c\u4f4e\u4e0b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u4ee5\u4e0a4\u3064\u306e\u4f5c\u7528\u3092\u7dcf\u5408\u3059\u308b\u3068\u3001\u4ee5\u4e0b\u306e\u56f3\u306b\u793a\u3059\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"650\" height=\"493\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/d6359c01897ba4a79b9906ae2ca1bc57-650x493-1.jpg\" alt=\"\" class=\"wp-image-144\" style=\"width:342px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/d6359c01897ba4a79b9906ae2ca1bc57-650x493-1.jpg 650w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2023\/11\/d6359c01897ba4a79b9906ae2ca1bc57-650x493-1-396x300.jpg 396w\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(\u5f15\u7528\uff1a<a href=\"https:\/\/passmed.co.jp\/di\/archives\/14586\" title=\"\">\u65b0\u85ac\u60c5\u5831\u30aa\u30f3\u30e9\u30a4\u30f3<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3053\u306e\u4e2d\u3067\u7279\u306b\u6ce8\u76ee\u3059\u3079\u304d\u4f5c\u7528\u306f\u3001\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u6570\u306e\u5897\u52a0\u3067\u3059\u30022\u578b\u7cd6\u5c3f\u75c5\u306f\u3001\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u6570\u3068\u305d\u306e\u6a5f\u80fd\u304c\u5f90\u3005\u306b\u6e1b\u5c11\u3057\u3066\u3044\u304f\u9032\u884c\u6027\u306e\u75c5\u6c17\u3067\u3042\u308a\u3001\u5b8c\u6cbb\u3059\u308b\u3053\u3068\u306e\u306a\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u3053\u306e\u554f\u984c\u3092\u6539\u5584\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u70b9\u3067\u753b\u671f\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u30012\u578b\u7cd6\u5c3f\u75c5\u3068\u8a3a\u65ad\u3055\u308c\u3066\u304b\u3089\u9577\u3044\u6642\u9593\u304c\u7d4c\u904e\u3057\u3066\u3044\u308b\u65b9\u306e\u5834\u5408\u3001\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u6570\u3068\u305d\u306e\u6a5f\u80fd\u306f\u3059\u3067\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u306e\u3053\u306e\u3088\u3046\u306a\u4f5c\u7528\u306e\u5229\u70b9\u3092\u3042\u307e\u308a\u4eab\u53d7\u3067\u304d\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u30012\u578b\u7cd6\u5c3f\u75c5\u3068\u8a3a\u65ad\u3055\u308c\u3001\u307e\u3060\u305d\u308c\u307b\u3069\u6642\u9593\u304c\u7d4c\u904e\u3057\u3066\u3044\u306a\u3044\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u6bd4\u8f03\u7684\u4fdd\u305f\u308c\u3066\u3044\u308b\uff09\u6bb5\u968e\u3067\u3001\u6700\u521d\u306b\u4f7f\u7528\u3059\u308b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u30c4\u30a4\u30df\u30fc\u30b0\u3092\u9078\u629e\u3059\u308b\u306e\u3082\u826f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u306b\u306f\u3044\u304f\u3064\u304b\u306e\u6b20\u70b9\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305a\u306f\u3001\u30c4\u30a4\u30df\u30fc\u30b0\u3068\u30e1\u30c8\u30b0\u30eb\u30b3\u3092\u540c\u6642\u306b\u5185\u670d\u3059\u308b\u3068\u526f\u4f5c\u7528\u304c\u751f\u3058\u3084\u3059\u3044\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u65e5\u672c\u4eba\u3092\u5bfe\u8c61\u306b\u884c\u3063\u305f\u81e8\u5e8a\u7814\u7a76\uff08TIMES 2\u8a66\u9a13\uff09\u3067\u306f\u3001\u3053\u306e2\u5264\u4f75\u7528\u304c\u539f\u56e0\u306725%\u306e\u60a3\u8005\u306b\u80c3\u8178\u969c\u5bb3\uff08\u60aa\u5fc3\u3084\u4e0b\u75e2\u306a\u3069\uff09\u304c\u751f\u3058\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full\/10.1111\/dom.14613\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full\/10.1111\/dom.14613<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30e1\u30c8\u30b0\u30eb\u30b3\u306f\u3001\u6b27\u7c73\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u307e\u305a\u521d\u3081\u306b\u4f7f\u7528\u3059\u3079\u304d\u85ac\u5264\uff08\u7b2c\u4e00\u9078\u629e\u85ac\uff09\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u3066\u304a\u308a\u3001\u65e5\u672c\u306e\u7cd6\u5c3f\u75c5\u60a3\u8005\u3055\u3093\u3067\u3082\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30e1\u30c8\u30b0\u30eb\u30b3\u3092\u3059\u3067\u306b\u5185\u670d\u3057\u3066\u3044\u308b\u60a3\u8005\u3055\u3093\u306b\u306f\u3001\u65b0\u305f\u306b\u30c4\u30a4\u30df\u30fc\u30b0\u3092\u8ffd\u52a0\u3057\u3065\u3089\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u307e\u305f\u3001\u814e\u81d3\u306e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u60a3\u8005\u3055\u3093\u306b\u306f\u4f7f\u7528\u304c\u5236\u9650\u3055\u308c\u307e\u3059\u3002\u30c4\u30a4\u30df\u30fc\u30b0\u306f\u814e\u81d3\u304b\u3089\u6392\u6cc4\u3055\u308c\u308b\u85ac\u5264\u3067\u3042\u308a\u3001\u814e\u6a5f\u80fd\u304c\u60aa\u3044\u5834\u5408\u306b\u4f7f\u7528\u3059\u308b\u3068\u30c4\u30a4\u30df\u30fc\u30b0\u306e\u8840\u4e2d\u6fc3\u5ea6\u304c\u904e\u5270\u306b\u4e0a\u6607\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u814e\u6a5f\u80fd\u306e\u8a55\u4fa1\u306b\u4f7f\u3046\u6307\u6a19\u3067\u3042\u308beGFR\uff08\u63a8\u7b97\u7cf8\u7403\u4f53\u6ffe\u904e\u91cf\uff09\u304c45\u672a\u6e80\u306e\u65b9\u306b\u5bfe\u3057\u3066\u306f\u4f7f\u7528\u304c\u7981\u5fcc\u3067\u306f\u306a\u3044\u3082\u306e\u306e\u3001\u63a8\u5968\u3055\u308c\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u70b9\u304c\u6b20\u70b9\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3055\u3089\u306b\u65e5\u672c\u3067\u3057\u304b\u4f7f\u7528\u3055\u308c\u3066\u3044\u306a\u3044\u65b0\u85ac\u3068\u3044\u3046\u3053\u3068\u3082\u3042\u308a\u3001\u73fe\u6642\u70b9\u3067\u306f\u9577\u671f\u7684\u306a\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306f\u5206\u304b\u3089\u306a\u3044\u3068\u3044\u3046\u554f\u984c\u3082\u3042\u308a\u307e\u3059\u3002 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