{"id":255,"date":"2024-03-17T01:00:00","date_gmt":"2024-03-16T16:00:00","guid":{"rendered":"https:\/\/nakano-dm.clinic\/blog\/?p=255"},"modified":"2024-03-10T18:33:03","modified_gmt":"2024-03-10T09:33:03","slug":"post-255","status":"publish","type":"post","link":"https:\/\/nakano-dm.clinic\/blog\/post-255\/","title":{"rendered":"4\u6708\u304b\u3089\u81ea\u5df1\u8ca0\u62c5\u984d\u304c\u9ad8\u984d\u3068\u306a\u308b\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n<p>\u4e2d\u91ce\u99c5\u524d\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af \u7cd6\u5c3f\u75c5\u30fb\u5185\u5206\u6ccc\u5185\u79d1\u306e\u9662\u9577\u306e\u5927\u5ead\u5065\u53f2\u3067\u3059\u3002\u4eca\u56de\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306e\u8a71\u984c\u306b\u3064\u3044\u3066\u53d6\u308a\u4e0a\u3052\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306f\u30012021\u5e7410\u6708\u304b\u3089\u5168\u984d\u516c\u8cbb\u8ca0\u62c5\u304c\u59cb\u307e\u308a\u307e\u3057\u305f\u304c\u30012023\u5e7410\u6708\u304b\u3089\u306f\u516c\u8cbb\u652f\u63f4\u306b\u5909\u66f4\u3055\u308c\u3001\u6cbb\u7642\u85ac\u306e\u8ca0\u62c5\u984d\u306f\u5e74\u9f62\u3084\u53ce\u5165\u306a\u3069\u306b\u5fdc\u3058\u30663000\uff5e9000\u5186\u306e\u81ea\u5df1\u8ca0\u62c5\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u3053\u306e\u516c\u8cbb\u652f\u63f4\u30822024\u5e743\u670831\u65e5\u3092\u3082\u3063\u3066\u7d42\u4e86\u3059\u308b\u3053\u3068\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u30014\u67081\u65e5\u304b\u3089\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306e\u30be\u30b3\u30fc\u30d0\uff08\u30a8\u30f3\u30b7\u30c8\u30ec\u30eb\u30d3\u30eb\u30d5\u30de\u30eb\u9178\uff09\u306f5185\uff5e15555\u5186\u3001\u30e9\u30b2\u30d6\u30ea\u30aa\uff08\u30e2\u30eb\u30cc\u30d4\u30e9\u30d3\u30eb\uff09\u306f9431\uff5e28293\u5186\u3001\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\uff08\u30cb\u30eb\u30de\u30c8\u30ec\u30eb\u30d3\u30eb\u30ea\u30c8\u30ca\u30d3\u30eb\uff09\u306f9902\uff5e29708\u5186\u3068\u306a\u308a\u307e\u3059\u3002 <\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3053\u306e\u5909\u66f4\u306b\u3088\u308a\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306e\u4f7f\u7528\u3092\u8003\u3048\u3066\u3057\u307e\u3046\u65b9\u3082\u3044\u308b\u304b\u3068\u601d\u3044\u307e\u3059\u3002\u4eca\u56de\u306f\u3001\u4eca\u5f8c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u3067\u3042\u308b\u30be\u30b3\u30fc\u30d0\u3001\u30e9\u30b2\u30d6\u30ea\u30aa\u3001\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\u3092\u3069\u306e\u3088\u3046\u306a\u65b9\u3067\u3042\u308c\u3070\u4f7f\u7528\u3092\u3059\u3059\u3081\u308b\u304b\u306b\u3064\u3044\u3066\u304a\u8a71\u3057\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/1975772-800x600.jpg\" alt=\"\" class=\"wp-image-256\" style=\"width:312px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/1975772-800x600.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/1975772-400x300.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/1975772.jpg 1600w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30be\u30b3\u30fc\u30d0\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p>\u30be\u30b3\u30fc\u30d0\u306f\u3001\u65e5\u672c\u3092\u542b\u3080\u30a2\u30b8\u30a2\u3067\u884c\u308f\u308c\u305f\u81e8\u5e8a\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u4f53\u5185\u306e\u30a6\u30a4\u30eb\u30b9\u91cf\u304c\u65e9\u304f\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3068\u75c7\u72b6\u304c\u306a\u304f\u306a\u308b\u307e\u3067\u306e\u6642\u9593\u304c\u7d041\u65e5\u77ed\u7e2e\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u30be\u30b3\u30fc\u30d0\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306e\u91cd\u75c7\u5316\u3092\u4e88\u9632\u3059\u308b\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u307b\u3068\u3093\u3069\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u60a3\u8005\u3055\u3093\u306f\u5165\u9662\u304c\u5fc5\u8981\u306a\u3044\u8efd\u75c7\u3067\u3042\u308a\u3001\u9ad8\u984d\u3068\u306a\u308b\u30be\u30b3\u30fc\u30d0\u3092\u4f7f\u7528\u305b\u305a\u3068\u3082\u901a\u5e38\u306e\u611f\u5192\u85ac\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u5341\u5206\u306a\u6cbb\u7642\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u3001\u30be\u30b3\u30fc\u30d0\u306e\u4f7f\u7528\u3092\u7a4d\u6975\u7684\u306b\u306f\u304a\u3059\u3059\u3081\u3057\u307e\u305b\u3093\u304c\u3001\u75c7\u72b6\u304c\u3064\u3089\u304f\u30661\u65e5\u3067\u3082\u65e9\u304f\u75c7\u72b6\u3092\u6539\u5584\u3055\u305b\u305f\u3044\u65b9\u306b\u306f\u6295\u4e0e\u3092\u691c\u8a0e\u3057\u3066\u3082\u826f\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30e9\u30b2\u30d6\u30ea\u30aa\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p>\u30e9\u30b2\u30d6\u30ea\u30aa\u306f\u3001\u7d4c\u53e3\u6295\u4e0e\u304c\u53ef\u80fd\u306a\u30ea\u30dc\u30cc\u30af\u30ec\u30aa\u30b7\u30c9\u30a2\u30ca\u30ed\u30b0\u3067\u3059\u3002\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u5897\u6b96\u3092\u6291\u3048\u308b\u85ac\u5264\u3067\u3001\u91cd\u75c7\u5316\u30ea\u30b9\u30af\u306e\u3042\u308b\u60a3\u8005\u3055\u3093\u306b\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3053\u306e\u85ac\u5264\u306f\u3001\u30aa\u30df\u30af\u30ed\u30f3\u682a\u6d41\u884c\u524d\u306b\u884c\u308f\u308c\u305fMOVe-OUT\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3092\u7d0430%\u6e1b\u5c11\u3055\u305b\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2116044\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2116044<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"411\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2116044_f2-800x411.jpeg\" alt=\"\" class=\"wp-image-257\" style=\"width:530px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2116044_f2-800x411.jpeg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2116044_f2-400x205.jpeg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2116044_f2.jpeg 1266w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(N Engl J Med 2022; 386:509-520)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30e9\u30b2\u30d6\u30ea\u30aa\u306f\u3001\u4f75\u7528\u3067\u304d\u306a\u3044\u85ac\u5264\u304c\u306a\u3044\u3053\u3068\u304b\u3089\u3001\u91cd\u75c7\u5316\u306e\u30ea\u30b9\u30af\u56e0\u5b50\uff08\u9ad8\u9f62\u3001\u55ab\u7159\u3001\u7cd6\u5c3f\u75c5\u306a\u3069\uff09\u3092\u6709\u3059\u308b\u8efd\u75c7\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u60a3\u8005\u3055\u3093\u306b\u5e83\u304f\u7528\u3044\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u30aa\u30df\u30af\u30ed\u30f3\u682a\u6d41\u884c\u5f8c\u306e\u5927\u898f\u6a21\u81e8\u5e8a\u7814\u7a76\u3067\u3042\u308bPANORAMIC\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u30e9\u30b2\u30d6\u30ea\u30aa\u306f\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u3067\u3042\u308b\u300c\u767a\u75c7\u3057\u3066\u304b\u308928\u65e5\u4ee5\u5185\u306e\u5165\u9662\u3068\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u300d\u3092\u6e1b\u3089\u3059\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002(<a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(22)02597-1\/fulltext\">https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(22)02597-1\/fulltext<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"196\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_05b-800x196.jpg\" alt=\"\" class=\"wp-image-258\" style=\"width:676px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_05b-800x196.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_05b-400x98.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_05b.jpg 957w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(\u51fa\u5178\uff1aMSD\u30db\u30fc\u30e0\u30da\u30fc\u30b8)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u3001\u4ee5\u524d\u304b\u3089\u91cd\u75c7\u5316\u4e88\u9632\u52b9\u679c\u304c\u671f\u5f85\u3057\u3065\u3089\u3044\u30e9\u30b2\u30d6\u30ea\u30aa\u306e\u4f7f\u7528\u306f\u3042\u307e\u308a\u304a\u3059\u3059\u3081\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u526f\u6b21\u8a55\u4fa1\u9805\u76ee\u3067\u3042\u308b\u300c\u75c7\u72b6\u7de9\u548c\u307e\u3067\u306e\u65e5\u6570\u300d\u306f\u30aa\u30df\u30af\u30ed\u30f3\u682a\u3067\u3042\u3063\u3066\u3082\u6709\u52b9\u6027\u3092\u793a\u3057\u3066\u3044\u308b\u306e\u3067\u3001\u30e9\u30b2\u30d6\u30ea\u30aa\u3092\u4f7f\u7528\u3057\u305f\u3044\u3068\u3044\u3046\u91cd\u75c7\u5316\u30ea\u30b9\u30af\u306e\u3042\u308b\u60a3\u8005\u3055\u3093\u306b\u306f\u51e6\u65b9\u3092\u691c\u8a0e\u3057\u3066\u3082\u826f\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"339\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_07-800x339.jpg\" alt=\"\" class=\"wp-image-259\" style=\"width:596px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_07-800x339.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_07-400x170.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/clinical-results_panoramic_07.jpg 974w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(\u51fa\u5178\uff1aMSD\u30db\u30fc\u30e0\u30da\u30fc\u30b8)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p>\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\u306f\u3001\u30cb\u30eb\u30de\u30c8\u30ec\u30eb\u30d3\u30eb\u3068\u30ea\u30c8\u30ca\u30d3\u30eb\u306e2\u3064\u306e\u85ac\u5264\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30cb\u30eb\u30de\u30c8\u30ec\u30eb\u30d3\u30eb\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30e1\u30a4\u30f3\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3092\u963b\u5bb3\u3057\u3001\u4e00\u65b9\u306e\u30ea\u30c8\u30ca\u30d3\u30eb\u306f\u30cb\u30eb\u30de\u30c8\u30ec\u30eb\u30d3\u30eb\u306e\u4f53\u5185\u3067\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3068\u3057\u3066\u306e\u52b9\u679c\u3092\u767a\u63ee\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\u306f\u3001\u30aa\u30df\u30af\u30ed\u30f3\u682a\u6d41\u884c\u524d\u306b\u884c\u308f\u308c\u305fEPIC-HR\u8a66\u9a13\u306b\u3088\u308b\u3068\u3001\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3092\u7d0489.1%\u6e1b\u5c11\u3055\u305b\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/nejmoa2118542\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/nejmoa2118542<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"197\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/image-800x197.jpg\" alt=\"\" class=\"wp-image-260\" style=\"width:645px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/image-800x197.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/image-400x99.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/image.jpg 1179w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(\u51fa\u5178\uff1aPfizer\u30db\u30fc\u30e0\u30da\u30fc\u30b8)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u3057\u3066\u3001\u30aa\u30df\u30af\u30ed\u30f3\u682a\u6d41\u884c\u5f8c\u306e\u5927\u898f\u6a21\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u3001\u4ee5\u524d\u306e\u30d6\u30ed\u30b0\u8a18\u4e8b\u300c<a href=\"https:\/\/nakano-dm.clinic\/blog\/post-82\" title=\"\">\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306f\u672c\u5f53\u306b\u52b9\u679c\u304c\u3042\u308b\u306e\uff1f<\/a>\u300d\u3067\u3082\u8ff0\u3079\u307e\u3057\u305f\u304c\u300165\u6b73\u672a\u6e80\u306e\u65b9\u3067\u306f\u6709\u52b9\u6027\u304c\u8a8d\u3081\u3089\u308c\u306a\u3044\u4e00\u65b9\u3067\u300165\u6b73\u4ee5\u4e0a\u306e\u65b9\u3067\u306f\u5165\u9662\u306e\u30ea\u30b9\u30af\u3092\u7d0473%\u6e1b\u5c11\u3055\u305b\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2204919\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2204919<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"207\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2204919_t3-800x207.jpeg\" alt=\"\" class=\"wp-image-261\" style=\"width:578px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2204919_t3-800x207.jpeg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2204919_t3-400x103.jpeg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/nejmoa2204919_t3.jpeg 893w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">(N Engl J Med 2022; 387:790-798)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089\u3001\u91cd\u75c7\u5316\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u6709\u3059\u308b65\u6b73\u672a\u6e80\u306e\u8efd\u75c7\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u60a3\u8005\u3055\u3093\u3078\u306e\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\u6295\u4e0e\u306f\u305d\u308c\u307b\u3069\u63a8\u5968\u3055\u308c\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u304c\u300165\u6b73\u4ee5\u4e0a\u306e\u65b9\u3001\u3082\u3057\u304f\u306f65\u6b73\u672a\u6e80\u3067\u3082\u514d\u75ab\u529b\u306e\u4f4e\u3044\u65b9\uff08\u30b9\u30c6\u30ed\u30a4\u30c9\u5185\u670d\u3084\u7cd6\u5c3f\u75c5\u306e\u65b9\u306a\u3069\uff09\u306b\u306f\u51e6\u65b9\u304c\u6709\u7528\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u3053\u308c\u304b\u3089\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u5ea6\u91cd\u306a\u308b\u5909\u7570\u306b\u3088\u3063\u3066\u91cd\u75c7\u5316\u3059\u308b\u30ea\u30b9\u30af\u304c\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u30be\u30b3\u30fc\u30d0\u3068\u30e9\u30b2\u30d6\u30ea\u30aa\u306b\u306f\u30aa\u30df\u30af\u30ed\u30f3\u682a\u306b\u5bfe\u3059\u308b\u91cd\u75c7\u5316\u4e88\u9632\u52b9\u679c\u3092\u8a8d\u3081\u306a\u3044\u306a\u3069\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306e\u52b9\u679c\u3082\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u300165\u6b73\u672a\u6e80\u306e\u65b9\u3067\u3042\u308c\u3070\u539f\u5247\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u6cbb\u7642\u85ac\u306f\u4e0d\u8981\u3068\u8003\u3048\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u91cd\u75c7\u5316\u306e\u30ea\u30b9\u30af\u306e\u3042\u308b65\u6b73\u4ee5\u4e0a\u306e\u65b9\u308465\u6b73\u672a\u6e80\u3067\u3082\u514d\u75ab\u529b\u306e\u4f4e\u3044\u65b9\u306b\u306f\u3001\u9ad8\u984d\u3067\u3042\u3063\u3066\u3082\u547d\u3092\u5b88\u308b\u305f\u3081\u306b\u30aa\u30df\u30af\u30ed\u30f3\u682a\u306b\u3082\u91cd\u75c7\u5316\u4e88\u9632\u52b9\u679c\u3092\u8a8d\u3081\u305f\u30d1\u30ad\u30ed\u30d3\u30c3\u30c9\u30d1\u30c3\u30af\u3092\u4f7f\u7528\u3059\u308b\u306e\u304c\u826f\u3044\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u6700\u8fd1\u306f\u3001\u30b3\u30ed\u30ca\u306e\u91cd\u75c7\u5316\u3060\u3051\u3067\u306a\u304f\u30b3\u30ed\u30ca\u5f8c\u907a\u75c7\uff08\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306e\u7f79\u60a3\u5f8c\u75c7\u72b6\uff09\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30b3\u30ed\u30ca\u5f8c\u907a\u75c7\u306f\u3001WHO\u306e\u5831\u544a\u306b\u3088\u308b\u3068\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306b\u611f\u67d3\u3057\u305f\u65b9\u306e\u7d0410\uff5e20%\u304c\u306a\u308b\u3068\u3055\u308c\u3066\u304a\u308a\u3001\u307e\u3060\u5341\u5206\u306a\u6cbb\u7642\u6cd5\u304c\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u3067\u3082\u30b3\u30ed\u30ca\u5f8c\u907a\u75c7\u306e\u6cbb\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u6cbb\u7642\u306b\u96e3\u6e0b\u3059\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306f\u767a\u75c7\u4e88\u9632\u3084\u91cd\u75c7\u5316\u4e88\u9632\u3060\u3051\u3067\u306a\u304f\u3001\u6700\u8fd1\u3067\u306f\u30b3\u30ed\u30ca\u5f8c\u907a\u75c7\u306e\u30ea\u30b9\u30af\u309243\uff05\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2802877\">https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2802877<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306e\u6709\u52b9\u6027\u306f\u6cbb\u7642\u85ac\u3068\u540c\u69d8\u306b\u3084\u3084\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3068\u63a8\u6e2c\u3055\u308c\u307e\u3059\u304c\u3001\u4e00\u65b9\u3067\u30b3\u30ed\u30ca\u5f8c\u907a\u75c7\u3092\u6e1b\u3089\u3059\u3053\u3068\u306f\u671f\u5f85\u3055\u308c\u308b\u305f\u3081\u3001\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u5f15\u304d\u7d9a\u304d\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u63a8\u5968\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u30d5\u30a1\u30a4\u30b6\u30fc\u3068\u7b2c\u4e00\u4e09\u5171\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3092\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u3002\u30ef\u30af\u30c1\u30f3\u306e\u5168\u984d\u516c\u8cbb\u306b\u3088\u308b\u63a5\u7a2e\u306f\u4eca\u6708\u672b\u3067\u7d42\u4e86\u3057\u307e\u3059\u306e\u3067\u3001\u307e\u3060\u30aa\u30df\u30af\u30ed\u30f3\u682aXBB.1.5\u7cfb\u7d71\u5bfe\u5fdc\u306e\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3055\u308c\u3066\u3044\u306a\u3044\u65b9\u306f\u304a\u65e9\u3081\u306b\u8ffd\u52a0\u63a5\u7a2e\u3055\u308c\u308b\u3053\u3068\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\uff08\u6587\u8cac\uff1a\u4e2d\u91ce\u99c5\u524d\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af \u7cd6\u5c3f\u75c5\u30fb\u5185\u5206\u6ccc\u5185\u79d1\u3000\u9662\u9577\u30fb\u533b\u5b66\u535a\u58eb\u3000\u5927\u5ead\u5065\u53f2\uff09<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/004n-800x533.jpg\" alt=\"\" class=\"wp-image-262\" style=\"width:578px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/004n-800x533.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2024\/03\/004n-400x267.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u91ce\u99c5\u524d\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af 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