{"id":457,"date":"2025-02-28T01:00:00","date_gmt":"2025-02-27T16:00:00","guid":{"rendered":"https:\/\/nakano-dm.clinic\/blog\/?p=457"},"modified":"2025-02-26T23:13:08","modified_gmt":"2025-02-26T14:13:08","slug":"post-457","status":"publish","type":"post","link":"https:\/\/nakano-dm.clinic\/blog\/post-457\/","title":{"rendered":"\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u5c02\u9580\u5bb6\u304c7\u3064\u306e\u9ad8\u8840\u5727\u75c7\u6cbb\u7642\u85ac\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac"},"content":{"rendered":"\n<p>\u4e2d\u91ce\u99c5\u524d\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af \u7cd6\u5c3f\u75c5\u30fb\u5185\u5206\u6ccc\u5185\u79d1\u306e\u9662\u9577\u306e\u5927\u5ead\u5065\u53f2\u3067\u3059\u3002\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u7532\u72b6\u817a\u75be\u60a3\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u5185\u5206\u6ccc\u75be\u60a3\u3092\u5c02\u9580\u306b\u8a3a\u7642\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u5185\u300c<a href=\"https:\/\/nakano-dm.clinic\/high_blood_pressure.html\" target=\"_blank\" rel=\"noopener\" title=\"\">\u9ad8\u8840\u5727\u75c7<\/a>\u300d\u306e\u30da\u30fc\u30b8\u3067\u306f\u3001\u9ad8\u8840\u5727\u75c7\u306e\u6cbb\u7642\u306e\u91cd\u8981\u6027\u306b\u3064\u3044\u3066\u3054\u8aac\u660e\u3057\u3066\u307e\u3044\u308a\u307e\u3057\u305f\u3002\u4eca\u56de\u306f\u30017\u3064\u306e\u9ad8\u8840\u5727\u75c7\u306e\u6cbb\u7642\u85ac\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u89e3\u8aac\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/166457-600x600.jpg\" alt=\"\" class=\"wp-image-458\" style=\"width:330px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/166457-600x600.jpg 600w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/166457-300x300.jpg 300w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/166457.jpg 1556w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">\u3000<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u9ad8\u8840\u5727\u75c7\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p>\u9ad8\u8840\u5727\u75c7\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u3084\u8133\u5352\u4e2d\u3001\u814e\u969c\u5bb3\u306a\u3069\u306e\u91cd\u5927\u306a\u5408\u4f75\u75c7\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u75be\u60a3\u3067\u3042\u308a\u3001\u9069\u5207\u306a\u6cbb\u7642\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>\u6cbb\u7642\u306e\u57fa\u672c\u306f\u3001\u6e1b\u5869\u30fb\u9069\u5ea6\u306a\u904b\u52d5\u30fb\u4f53\u91cd\u7ba1\u7406\u30fb\u7981\u7159\u30fb\u7bc0\u9152\u3068\u3044\u3063\u305f\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584<\/strong>\u3067\u3059\u304c\u3001\u3053\u308c\u3060\u3051\u3067\u306f\u5341\u5206\u306a\u964d\u5727\u304c\u5f97\u3089\u308c\u306a\u3044\u5834\u5408\u3001<strong>\u85ac\u7269\u7642\u6cd5\u304c\u5fc5\u8981<\/strong>\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"569\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/26140992-800x569.jpg\" alt=\"\" class=\"wp-image-459\" style=\"width:401px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/26140992-800x569.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/26140992-400x285.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/26140992.jpg 1600w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u9ad8\u8840\u5727\u75c7\u6cbb\u7642\u85ac\u306b\u306f\u3055\u307e\u3056\u307e\u306a\u7a2e\u985e\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u4f5c\u7528\u6a5f\u5e8f\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5358\u5264\u3067\u306f\u5341\u5206\u306a\u964d\u5727\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u3044\u5834\u5408\u3001\u7570\u306a\u308b\u6a5f\u5e8f\u306e\u85ac\u5264\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u964d\u5727\u3084\u526f\u4f5c\u7528\u306e\u8efd\u6e1b\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u4e3b\u306a\u9ad8\u8840\u5727\u75c7\u6cbb\u7642\u85ac\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u306e\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac<\/p>\n\n\n\n<p>\u30fb\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09<\/p>\n\n\n\n<p>\u30fb\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u85ac\uff08ACE\u963b\u5bb3\u85ac\uff09<\/p>\n\n\n\n<p>\u30fb\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\uff08ARNI\uff09<\/p>\n\n\n\n<p>\u30fb\u5229\u5c3f\u85ac<\/p>\n\n\n\n<p>\u30fb\u03b2\u906e\u65ad\u85ac<\/p>\n\n\n\n<p>\u30fb\u03b1\u906e\u65ad\u85ac<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u6b21\u306b\u3001\u305d\u308c\u305e\u308c\u306e\u964d\u5727\u85ac\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/330474-800x600.jpg\" alt=\"\" class=\"wp-image-460\" style=\"width:315px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/330474-800x600.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/330474-400x300.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/02\/330474.jpg 1600w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\uff08CCB\uff09<\/strong><\/h2>\n\n\n\n<p>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u306f\u3001\u8840\u7ba1\u5e73\u6ed1\u7b4b\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\u3092\u906e\u65ad\u3059\u308b\u3053\u3068\u3067\u8840\u7ba1\u3092\u62e1\u5f35\u3055\u305b\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3053\u306e\u85ac\u5264\u306f\u3001\u4f5c\u7528\u306e\u9055\u3044\u306b\u3088\u308a\u3001\u8840\u7ba1\u9078\u629e\u6027\u304c\u9ad8\u304f\u4e3b\u306b\u8840\u7ba1\u3092\u62e1\u5f35\u3055\u305b\u308b\u30b8\u30d2\u30c9\u30ed\u30d4\u30ea\u30b8\u30f3\u7cfb\u3068\u3001\u5fc3\u81d3\u3078\u306e\u5f71\u97ff\u304c\u5f37\u304f\u5fc3\u53ce\u7e2e\u529b\u3092\u6291\u3048\u3001\u8108\u62cd\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u975e\u30b8\u30d2\u30c9\u30ed\u30d4\u30ea\u30b8\u30f3\u7cfb\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u9ad8\u8840\u5727\u306e\u6cbb\u7642\u3067\u306f\u3001\u4e3b\u306b\u30b8\u30d2\u30c9\u30ed\u30d4\u30ea\u30b8\u30f3\u7cfb\u306e\u30a2\u30e0\u30ed\u30b8\u30f3\u3001\u30a2\u30c0\u30e9\u30fc\u30c8\u3001\u30a2\u30c6\u30ec\u30c3\u30af\u306a\u3069\u304c\u7528\u3044\u3089\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u85ac\u5264\u306f\u3001<strong>\u964d\u5727\u52b9\u679c\u304c\u9ad8\u304f\u3001\u526f\u4f5c\u7528\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u3044<\/strong>\u305f\u3081\u3001<strong>\u9ad8\u8840\u5727\u75c7\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u7b2c\u4e00\u9078\u629e\u3068\u306a\u308b\u3053\u3068\u304c\u591a\u3044<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u624b\u8db3\u306e\u6d6e\u816b<\/p>\n\n\n\n<p>\u30fb\u982d\u75db<\/p>\n\n\n\n<p>\u30fb\u3081\u307e\u3044<\/p>\n\n\n\n<p>\u30fb\u52d5\u60b8\u3084\u983b\u8108<\/p>\n\n\n\n<p>\u30fb\u9854\u9762\u306e\u7d05\u6f6e<\/p>\n\n\n\n<p>\u30fb\u4fbf\u79d8<\/p>\n\n\n\n<p>\u30fb\u6b6f\u8089\u80a5\u539a<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306f\u3001\u4e3b\u306b\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u30bf\u30a4\u30d71\u53d7\u5bb9\u4f53\u3092\u906e\u65ad\u3057\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u306b\u3088\u308b\u8840\u7ba1\u53ce\u7e2e\u4f5c\u7528\u3084\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u8840\u5727\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>ROADMAP\u8a66\u9a13\u306b\u3088\u308a\u3001\u3053\u306e\u85ac\u5264\u304c2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3055\u3093\u306e\u7cd6\u5c3f\u75c5\u814e\u75c7\u306e\u9032\u884c\u3092\u4e88\u9632\u3059\u308b\u52b9\u679c\u3092\u6301\u3064\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u305f\u3081\u3001<strong>\u7cd6\u5c3f\u75c5\u814e\u75c7\u7b2c2\u671f\u4ee5\u4e0a\u306e\u7cd6\u5c3f\u75c5\u60a3\u8005\u3055\u3093\u306b\u306f\u7b2c\u4e00\u9078\u629e\u85ac\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059<\/strong>\u3002(<a href=\"https:\/\/www.nejm.jp\/abstract\/vol364.p907\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/www.nejm.jp\/abstract\/vol364.p907<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u964d\u5727\u52b9\u679c\u306e\u5f37\u3055\u306f\u3001\u30a2\u30b8\u30eb\u30d0\u3001\u30aa\u30eb\u30e1\u30c6\u30c3\u30af\u3001\u30df\u30ab\u30eb\u30c7\u30a3\u30b9\u3001\u30a2\u30d0\u30d7\u30ed\u3001\u30d6\u30ed\u30d7\u30ec\u30b9\u3001\u30c7\u30a3\u30aa\u30d0\u30f3\u3001\u30cb\u30e5\u30fc\u30ed\u30bf\u30f3\u306e\u9806\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u304a\u308a\u3001\u6cbb\u7642\u62b5\u6297\u6027\u9ad8\u8840\u5727\u306e\u60a3\u8005\u306b\u306f\u3001\u3088\u308a\u5f37\u529b\u306a\u30a2\u30b8\u30eb\u30d0\u3084\u30aa\u30eb\u30e1\u30c6\u30c3\u30af\u304c\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7<\/p>\n\n\n\n<p>\u30fb\u814e\u6a5f\u80fd\u969c\u5bb3<\/p>\n\n\n\n<p>\u30fb\u982d\u75db<\/p>\n\n\n\n<p>\u30fb\u3081\u307e\u3044<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u85ac\uff08ACE\u963b\u5bb3\u85ac\uff09<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u85ac\u306f\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3I\u304b\u3089\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u3078\u306e\u5909\u63db\u3092\u963b\u5bb3\u3057\u3001\u8840\u5727\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u52b9\u679c\u3092\u6301\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u30ad\u30cb\u30ca\u30fc\u30bc\u306e\u963b\u5bb3\u306b\u3088\u308a\u8840\u4e2d\u30d6\u30e9\u30b8\u30ad\u30cb\u30f3\u304c\u4e0a\u6607\u3057\u3001\u8840\u7ba1\u62e1\u5f35\u4f5c\u7528\u304c\u5f37\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u30d6\u30e9\u30b8\u30ad\u30cb\u30f3\u306b\u306f\u8840\u7ba1\u900f\u904e\u6027\u3092\u9ad8\u3081\u308b\u4f5c\u7528\u304c\u3042\u308b\u305f\u3081\u3001\u8840\u7ba1\u6d6e\u816b\u3092\u5f15\u304d\u8d77\u3053\u3057\u3084\u3059\u304f\u3001\u307e\u305f\u6c17\u9053\u3092\u523a\u6fc0\u3059\u308b\u3053\u3068\u3067\u54b3\u304c\u751f\u3058\u3084\u3059\u304f\u306a\u308b\u3068\u3044\u3063\u305f\u526f\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u3001\u3053\u306e\u85ac\u5264\u306e\u4f7f\u7528\u306f\u8fd1\u5e74\u6e1b\u5c11\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u304c\u3001\u4e00\u65b9\u3067\u3001\u54b3\u304c\u8a98\u767a\u3055\u308c\u308b\u3053\u3068\u3067<strong>\u8aa4\u56a5\u3092\u9632\u3050\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong>\u305f\u3081\u3001\u9ad8\u9f62\u8005\u306b\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u85ac\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u7a7a\u54b3<\/p>\n\n\n\n<p>\u30fb\u8840\u7ba1\u6d6e\u816b<\/p>\n\n\n\n<p>\u30fb\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7<\/p>\n\n\n\n<p>\u30fb\u814e\u6a5f\u80fd\u969c\u5bb3<\/p>\n\n\n\n<p>\u30fb\u982d\u75db<\/p>\n\n\n\n<p>\u30fb\u3081\u307e\u3044<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\uff08ARNI\uff09<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\u3067\u3042\u308b\u30a8\u30f3\u30ec\u30b9\u30c8\u306f\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3068\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u8840\u7ba1\u62e1\u5f35\u4f5c\u7528\u3084\u5229\u5c3f\u4f5c\u7528\u3092\u6709\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u5f53\u521d\u306f\u5fc3\u4e0d\u5168\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u307f\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u305d\u306e\u5f8c\u3001<strong>\u5f37\u529b\u306a\u964d\u5727\u4f5c\u7528<\/strong>\u304c\u8a8d\u3081\u3089\u308c\u30012021\u5e74\u306b\u9ad8\u8840\u5727\u75c7\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u3082\u627f\u8a8d\u3055\u308c\u3001\u4f7f\u7528\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u9ad8\u8840\u5727\u75c7\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u306f\u7b2c\u4e00\u9078\u629e\u85ac\u3068\u306f\u306a\u3089\u305a\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3082\u5341\u5206\u306b\u8840\u5727\u304c\u4f4e\u4e0b\u3057\u306a\u3044\u5834\u5408\u306a\u3069\u306b\u9650\u308a\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7<\/p>\n\n\n\n<p>\u30fb\u8840\u5727\u4f4e\u4e0b<\/p>\n\n\n\n<p>\u30fb\u814e\u6a5f\u80fd\u969c\u5bb3<\/p>\n\n\n\n<p>\u30fb\u8840\u7ba1\u6d6e\u816b<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u5229\u5c3f\u85ac<\/strong><\/h2>\n\n\n\n<p>\u5229\u5c3f\u85ac\u306f\u814e\u81d3\u306b\u4f5c\u7528\u3057\u3001\u30ca\u30c8\u30ea\u30a6\u30e0\u3068\u6c34\u306e\u6392\u6cc4\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u3067\u5faa\u74b0\u8840\u6db2\u91cf\u3092\u6e1b\u5c11\u3055\u305b\u3001\u8840\u5727\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5229\u5c3f\u85ac\u306f\u3001\u30df\u30cd\u30e9\u30eb\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08\u30df\u30cd\u30d6\u30ed\u3001\u30bb\u30e9\u30e9\u3001\u30a2\u30eb\u30c0\u30af\u30c8\u30f3\uff09\u3001\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac\uff08\u30d5\u30eb\u30a4\u30c8\u30e9\u30f3\u3001\u30ca\u30c8\u30ea\u30c3\u30af\u30b9\uff09\u3001\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac\uff08\u30e9\u30b7\u30c3\u30af\u30b9\u3001\u30c0\u30a4\u30a2\u30fc\u30c8\u3001\u30eb\u30d7\u30e9\u30c3\u30af\uff09\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>\u30df\u30cd\u30e9\u30eb\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306f\u539f\u767a\u6027\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u75c7\u306e\u6cbb\u7642\u306b\u3088\u304f\u4f7f\u7528\u3055\u308c<\/strong>\u3001<strong>\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac\u306f\u5869\u5206\u3092\u591a\u304f\u6442\u53d6\u3059\u308b\u4eba\u306b\u9069\u3057\u3066\u3044\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac\u306b\u95a2\u3057\u3066\u306f\u3001\u6162\u6027\u5fc3\u4e0d\u5168\u306e\u4e88\u5f8c\u3092\u60aa\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u306e\u5831\u544a\u3084\u3001\u4f7f\u7528\u91cf\u304c\u591a\u3044\u307b\u3069\u4e88\u5f8c\u304c\u60aa\u5316\u3059\u308b\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002(<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16709595\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16709595<\/a>)(<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16765130\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16765130<\/a>)<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac\u306f\u5f37\u529b\u306a\u5229\u5c3f\u4f5c\u7528\u3092\u6301\u3064\u305f\u3081\u3001\u9ad8\u8840\u5727\u75c7\u5358\u72ec\u306e\u6cbb\u7642\u76ee\u7684\u3067\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u306f\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5229\u5c3f\u85ac\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7<\/p>\n\n\n\n<p>\u30fb\u8131\u6c34<\/p>\n\n\n\n<p>\u30fb\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\uff08\u30df\u30cd\u30e9\u30eb\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff09<\/p>\n\n\n\n<p>\u30fb\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\uff08\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u3068\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac\uff09<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u03b2\u906e\u65ad\u85ac<\/strong><\/h2>\n\n\n\n<p>\u03b2\u906e\u65ad\u85ac\u306f\u3001\u4ea4\u611f\u795e\u7d4c\u306e\u03b2\u53d7\u5bb9\u4f53\u3092\u906e\u65ad\u3059\u308b\u3053\u3068\u3067\u5fc3\u62cd\u6570\u3092\u6e1b\u5c11\u3055\u305b\u3001\u8840\u5727\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u964d\u5727\u52b9\u679c\u306f\u6bd4\u8f03\u7684\u5f31\u3044\u305f\u3081\u3001\u9ad8\u8840\u5727\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u5358\u72ec\u3067\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u306f\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u3067\u3059\u304c\u3001<strong>\u5b89\u5b9a\u3057\u305f\u6162\u6027\u5fc3\u4e0d\u5168\u3084\u983b\u8108\u6027\u4e0d\u6574\u8108\u3092\u5408\u4f75\u3059\u308b\u9ad8\u8840\u5727\u60a3\u8005\u3055\u3093\u306b\u306f\u3088\u304f\u4f7f\u7528\u3055\u308c\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u03b2\u906e\u65ad\u85ac\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u5f90\u8108<\/p>\n\n\n\n<p>\u30fb\u6c17\u7ba1\u652f\u53ce\u7e2e\uff08\u5598\u606f\u60a3\u8005\u3055\u3093\u3067\u306f\u7981\u5fcc\uff09<\/p>\n\n\n\n<p>\u30fb\u56db\u80a2\u51b7\u611f<\/p>\n\n\n\n<p>\u30fb\u5026\u6020\u611f<\/p>\n\n\n\n<p>\u30fb\u3081\u307e\u3044<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. 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