{"id":482,"date":"2025-03-31T01:12:00","date_gmt":"2025-03-30T16:12:00","guid":{"rendered":"https:\/\/nakano-dm.clinic\/blog\/?p=482"},"modified":"2025-03-29T22:45:57","modified_gmt":"2025-03-29T13:45:57","slug":"post-482","status":"publish","type":"post","link":"https:\/\/nakano-dm.clinic\/blog\/post-482\/","title":{"rendered":"2025\u5e744\u670811\u65e5\u767a\u58f2\u306e\u80a5\u6e80\u75c7\u6cbb\u7642\u85ac\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306b\u3064\u3044\u3066\u89e3\u8aac\uff01"},"content":{"rendered":"\n

\u6771\u4eac\u306eJR\u4e2d\u91ce\u99c5\u5357\u53e3\u304b\u3089\u3059\u3050\u306e\u5834\u6240\u306b\u3042\u308b\u300c\u4e2d\u91ce\u99c5\u524d\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af \u7cd6\u5c3f\u75c5\u30fb\u5185\u5206\u6ccc\u5185\u79d1\u300d\u306e\u9662\u9577\u3001\u5927\u5ead\u5065\u53f2\u3067\u3059\u3002\u79c1\u306f\u3001\u7cd6\u5c3f\u75c5\u5c02\u9580\u533b\u304a\u3088\u3073\u5185\u5206\u6ccc\u4ee3\u8b1d\u79d1\u5c02\u9580\u533b\u3068\u3057\u3066\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u306e\u30d6\u30ed\u30b0 \u300c2024\u5e7412\u670827\u65e5\u306b\u88fd\u9020\u8ca9\u58f2\u627f\u8a8d\u3055\u308c\u305f\u80a5\u6e80\u75c7\u6cbb\u7642\u85ac\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3068\u306f<\/a>\u300d\u3067\u3082\u53d6\u308a\u4e0a\u3052\u305f GIP\/GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u300c\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u300d \u304c\u3001\u3044\u3088\u3044\u30882024\u5e744\u670811\u65e5\u306b\u767a\u58f2\u3055\u308c\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3055\u3089\u306b\u3001\u3059\u3067\u306b2025\u5e743\u670818\u65e5\u306b\u306f\u3001\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306b\u95a2\u3059\u308b\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u304c\u516c\u8868\u3055\u308c\u3001\u5bfe\u8c61\u3068\u306a\u308b\u60a3\u8005\u3055\u3093\u3084\u51e6\u65b9\u53ef\u80fd\u306a\u533b\u7642\u6a5f\u95a2\u304c\u660e\u78ba\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u305d\u3053\u3067\u4eca\u56de\u306f\u3001\u80a5\u6e80\u75c7\u6cbb\u7642\u3092\u5927\u304d\u304f\u5909\u3048\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306b\u3064\u3044\u3066\u3001\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\uff08\u51fa\u5178\uff1a\u7530\u8fba\u4e09\u83f1\u88fd\u85ac\u30db\u30fc\u30e0\u30da\u30fc\u30b8\uff09<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3068\u306f<\/strong><\/h2>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306f\u30012022\u5e746\u6708\u306b\u30a2\u30e1\u30ea\u30ab\u3067\u767a\u58f2\u3055\u308c\u3001\u65e5\u672c\u3067\u306f2023\u5e744\u6708\u306b\u767a\u58f2\u3055\u308c\u305f2\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u300c\u30de\u30f3\u30b8\u30e3\u30ed\uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff09\u300d\u306e\u9069\u5fdc\u3092\u3001\u80a5\u6e80\u75c7\u60a3\u8005\u5411\u3051\u306b\u62e1\u5927\u3057\u305f\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3053\u306e\u85ac\u5264\u306f\u3001\u4e3b\u306b\u5c0f\u8178\u304b\u3089\u5206\u6ccc\u3055\u308c\u308bGIP\uff08\u30b0\u30eb\u30b3\u30fc\u30b9\u4f9d\u5b58\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u523a\u6fc0\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\uff09\u306e\u30da\u30d7\u30c1\u30c9\u914d\u5217\u3092\u30d9\u30fc\u30b9\u306b\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3055\u3089\u306b\u3001GIP\u53d7\u5bb9\u4f53\u3060\u3051\u3067\u306a\u304fGLP-1\u53d7\u5bb9\u4f53\u306b\u3082\u9577\u6642\u9593\u4f5c\u7528\u3059\u308b\u7279\u6027\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002 \u305d\u306e\u7d50\u679c\u3001\u8840\u7cd6\u6539\u5584\u52b9\u679c\u3084\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u306f\u3001\u30a6\u30b4\u30fc\u30d3\u3092\u542b\u3080\u65e2\u5b58\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u4e0a\u56de\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u6b21\u306b\u3001\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n

\u30a2\u30e1\u30ea\u30ab\u306e\u30a4\u30a7\u30fc\u30eb\u5927\u5b66\u306eJastreboff\u3089\u304c\u5b9f\u65bd\u3057\u305f\u5927\u898f\u6a21\u81e8\u5e8a\u7814\u7a76\uff08SURMOUNT-1\uff09\u306b\u3088\u308b\u3068\u3001\u6cbb\u7642\u958b\u59cb\u304b\u308972\u9031\u5f8c\u306e\u4f53\u91cd\u5909\u5316\u91cf\u306f\u3001\u98df\u4e8b\u7642\u6cd5\u3068\u904b\u52d5\u7642\u6cd5\u306e\u307f\u3092\u884c\u3063\u305f\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067\u306f3.1%\u306e\u6e1b\u5c11\u306b\u3068\u3069\u307e\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u4e00\u65b9\u3067\u3001\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3092\u4f7f\u7528\u3057\u305f\u7fa4\u3067\u306f\u30015 mg\u6295\u4e0e\u7fa4\u306715.0%\u300110 mg\u6295\u4e0e\u7fa4\u306719.5%\u300115 mg\u6295\u4e0e\u7fa4\u306720.9%\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u307e\u305f\u3001\u4f53\u91cd5%\u4ee5\u4e0a\u306e\u6e1b\u91cf\u3092\u9054\u6210\u3057\u305f\u5272\u5408\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u304c34.5%\u3060\u3063\u305f\u306e\u306b\u5bfe\u3057\u30015 mg\u7fa4\u306f85.1%\u300110 mg\u7fa4\u306f88.9%\u300115 mg\u7fa4\u306f90.9%\u3068\u6709\u610f\u306a\u6539\u5584\u3092\u8a8d\u3081\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3055\u3089\u306b\u3001\u4f53\u91cd20%\u4ee5\u4e0a\u306e\u6e1b\u91cf\u3092\u9054\u6210\u3057\u305f\u5272\u5408\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u304c3.1%\u3060\u3063\u305f\u306e\u306b\u5bfe\u3057\u30015 mg\u7fa4\u306f30.0%\u300110 mg\u7fa4\u306f50.1%\u300115 mg\u7fa4\u306f56.7%\u3068\u6709\u610f\u306a\u6539\u5584\u3092\u8a8d\u3081\u307e\u3057\u305f\u3002(https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038<\/a>)<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

SURMOUNT-1\u7814\u7a76\u306f\u512a\u308c\u305f\u6210\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u304c\u3001\u5bfe\u8c61\u3068\u306a\u3063\u305f\u60a3\u8005\u306e\u307b\u3068\u3093\u3069\u304c\u6b27\u7c73\u4eba\u3067\u3042\u308a\u3001\u7814\u7a76\u53c2\u52a0\u8005\u306e\u5e73\u5747\u4f53\u91cd\u306f104.8 kg\u3001\u5e73\u5747BMI\u306f38.0 kg\/m\u00b2\u3067\u3057\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u9ad8\u5ea6\u80a5\u6e80\u75c7\u306e\u5c11\u306a\u3044\u65e5\u672c\u4eba\u306b\u304a\u3044\u3066\u540c\u69d8\u306e\u6709\u52b9\u6027\u304c\u767a\u63ee\u3055\u308c\u308b\u304b\u306f\u4e0d\u660e\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3053\u306e\u7591\u554f\u306b\u5fdc\u3048\u308b\u305f\u3081\u306b\u5b9f\u65bd\u3055\u308c\u305f\u306e\u304c\u3001\u65e5\u672c\u4eba\u306e\u80a5\u6e80\u75c7\u60a3\u8005\u3055\u3093\u3092\u5bfe\u8c61\u3068\u3057\u305f\u300cSURMOUNT-J\u7814\u7a76\u300d\u3067\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u6cbb\u7642\u958b\u59cb\u304b\u308972\u9031\u5f8c\u306e\u4f53\u91cd\u5909\u5316\u91cf\u3092\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067\u306f1.7%\u306e\u6e1b\u5c11\u306b\u3068\u3069\u307e\u308a\u307e\u3057\u305f\u304c\u3001\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c910 mg\u6295\u4e0e\u7fa4\u3067\u306f17.8%\u300115 mg\u6295\u4e0e\u7fa4\u3067\u306f22.7%\u306e\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u307e\u305f\u3001\u4f53\u91cd5%\u4ee5\u4e0a\u306e\u6e1b\u91cf\u3092\u9054\u6210\u3057\u305f\u5272\u5408\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u306720.0%\u3060\u3063\u305f\u306e\u306b\u5bfe\u3057\u300110 mg\u7fa4\u3067\u306f94.4%\u300115 mg\u7fa4\u3067\u306f96.1%\u3068\u6709\u610f\u306a\u6539\u5584\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3055\u3089\u306b\u3001\u4f53\u91cd20%\u4ee5\u4e0a\u306e\u6e1b\u91cf\u3092\u9054\u6210\u3057\u305f\u5272\u5408\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067\u306f0.0%\u3060\u3063\u305f\u306e\u306b\u5bfe\u3057\u300110 mg\u7fa4\u3067\u306f39.4%\u300115 mg\u7fa4\u3067\u306f64.5%\u3068\u3001\u5927\u5e45\u306a\u6539\u5584\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002(https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2213858724003772<\/a>) <\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306f\u6b27\u7c73\u4eba\u3060\u3051\u3067\u306a\u304f\u65e5\u672c\u4eba\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u672c\u5264\u306f\u65e5\u672c\u3067\u3082\u88fd\u9020\u627f\u8a8d\u3055\u308c\u30014\u670811\u65e5\u3088\u308a\u767a\u58f2\u3055\u308c\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u304c\u4f7f\u7528\u3067\u304d\u308b\u65b9\u306f\uff1f<\/strong><\/h2>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3092\u4f7f\u7528\u3067\u304d\u308b\u65b9\u306f\u3001\u6628\u5e74\u767a\u58f2\u3055\u308c\u305f\u30a6\u30b4\u30fc\u30d3\uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09\u3068\u540c\u69d8\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u9ad8\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u53c8\u306f2\u578b\u7cd6\u5c3f\u75c5\u306e\u3044\u305a\u308c\u304b\u3092\u6709\u3059\u308b\u80a5\u6e80\u75c7\u304c\u3042\u308a\u3001\u304b\u3064\u98df\u4e8b\u30fb\u904b\u52d5\u7642\u6cd5\u3092\u884c\u3063\u3066\u3082\u5341\u5206\u306a\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u304420\u6b73\u4ee5\u4e0a\u306e\u3046\u3061\u3001\u9ad8\u5ea6\u80a5\u6e80\u75c7\uff08BMI\u226735 kg\/m2<\/sup>\uff09\u3001\u3082\u3057\u304f\u306f\u4ee5\u4e0b\u306e\u793a\u3059\u80a5\u6e80\u306b\u95a2\u9023\u3059\u308b\u5065\u5eb7\u969c\u5bb3\u30922\u3064\u4ee5\u4e0a\u6709\u3059\u308b BMI\u226727 kg\/m2<\/sup>\u304c\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u4f7f\u7528\u306e\u5bfe\u8c61\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u30fb\u8010\u7cd6\u80fd\u969c\u5bb3 \uff082\u578b\u7cd6\u5c3f\u75c5\u3001\u8010\u7cd6\u80fd\u7570\u5e38\u306a\u3069\uff09<\/p>\n\n\n\n

\u30fb\u8102\u8cea\u7570\u5e38\u75c7<\/p>\n\n\n\n

\u30fb\u9ad8\u8840\u5727<\/p>\n\n\n\n

\u30fb\u9ad8\u5c3f\u9178\u8840\u75c7\u3001\u75db\u98a8<\/p>\n\n\n\n

\u30fb\u51a0\u52d5\u8108\u75be\u60a3\uff08\u5fc3\u7b4b\u6897\u585e\u3001\u72ed\u5fc3\u75c7\uff09<\/p>\n\n\n\n

\u30fb\u8133\u6897\u585e\u3001\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c<\/p>\n\n\n\n

\u30fb\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u6027\u809d\u75be\u60a3<\/p>\n\n\n\n

\u30fb\u6708\u7d4c\u7570\u5e38\u3001\u5973\u6027\u4e0d\u598a<\/p>\n\n\n\n

\u30fb\u9589\u585e\u6027\u7761\u7720\u6642\u7121\u547c\u5438\u75c7\u5019\u7fa4\u3001\u80a5\u6e80\u4f4e\u63db\u6c17\u75c7\u5019\u7fa4<\/p>\n\n\n\n

\u30fb\u904b\u52d5\u5668\u75be\u60a3\uff08\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u3001\u5909\u5f62\u6027\u810a\u690e\u75c7\uff09 <\/p>\n\n\n\n

\u30fb\u80a5\u6e80\u95a2\u9023\u814e\u81d3\u75c5<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3092\u51e6\u65b9\u3067\u304d\u307e\u305b\u3093\u304c\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u65b9\u306b\u306f\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u51e6\u65b9\u3057\u3001\u305d\u308c\u4ee5\u5916\u306e\u65b9\u306b\u3064\u3044\u3066\u306f\u533b\u7642\u9023\u643a\u3092\u7d50\u3093\u3067\u3044\u308b\u9ad8\u5ea6\u533b\u7642\u6a5f\u95a2\u3078\u3054\u7d39\u4ecb\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3092\u4f7f\u7528\u3059\u3079\u304d\u4eba\u306f\uff1f<\/strong><\/h2>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306f\u3001\u65b0\u85ac\u306e\u305f\u3081\u767a\u58f2\u304b\u3089\u7d041\u5e74\u9593\u306f2\u9031\u9593\u5206\u3057\u304b\u51e6\u65b9\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u307e\u305f\u3001\u985e\u4f3c\u85ac\u3067\u3042\u308b\u30a6\u30b4\u30fc\u30d3\u304c\u65e2\u306b\u4f7f\u7528\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u4eca\u3059\u3050\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3067\u6cbb\u7642\u3092\u958b\u59cb\u3059\u3079\u304d\u60a3\u8005\u3055\u3093\u306f\u9650\u3089\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002 <\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u79c1\u500b\u4eba\u306e\u898b\u89e3\u3067\u3059\u304c\u3001\u307e\u305a\u306f\u534a\u5e74\u4ee5\u4e0a\u306b\u308f\u305f\u308b\u6804\u990a\u6307\u5c0e\u3092\u53d7\u3051\u3001\u305d\u308c\u3067\u3082\u6539\u5584\u304c\u898b\u3089\u308c\u306a\u3044\u5834\u5408\u306b\u30a6\u30b4\u30fc\u30d3\u306b\u3088\u308b\u6cbb\u7642\u3092\u691c\u8a0e\u3059\u308b\u306e\u304c\u9069\u5207\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u306e\u767a\u58f2\u306b\u3088\u308b\u671f\u5f85\u3068\u8ab2\u984c<\/strong><\/h2>\n\n\n\n

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\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u6709\u52b9\u6027\u306e\u9ad8\u3044\u80a5\u6e80\u75c7\u6cbb\u7642\u85ac\u3067\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u304c\u5927\u898f\u6a21\u533b\u7642\u6a5f\u95a2\u3067\u306e\u307f\u51e6\u65b9\u53ef\u80fd\u306a\u73fe\u72b6\u306f\u975e\u5e38\u306b\u6b8b\u5ff5\u3067\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

<\/p>\n\n\n\n

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