{"id":619,"date":"2025-10-11T10:15:16","date_gmt":"2025-10-11T01:15:16","guid":{"rendered":"https:\/\/nakano-dm.clinic\/blog\/?p=619"},"modified":"2025-10-11T10:15:16","modified_gmt":"2025-10-11T01:15:16","slug":"post-619","status":"publish","type":"post","link":"https:\/\/nakano-dm.clinic\/blog\/post-619\/","title":{"rendered":"9\u670819\u65e5\u306b\u88fd\u9020\u8ca9\u58f2\u627f\u8a8d\u3055\u308c\u305f\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u6cbb\u7642\u85ac\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u3068\u306f"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u4e2d\u91ce\u99c5\u524d\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af \u7cd6\u5c3f\u75c5\u30fb\u5185\u5206\u6ccc\u5185\u79d1 \u9662\u9577\u306e\u5927\u5ead\u5065\u53f2\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u306e\u300c<a href=\"https:\/\/nakano-dm.clinic\/dyslipidemia.html\" title=\"\">\u8102\u8cea\u7570\u5e38\u75c7<\/a>\u300d\u3084\u30d6\u30ed\u30b0\u3067\u306f\u3001\u3053\u308c\u307e\u3067\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306e\u6cbb\u7642\u306e\u91cd\u8981\u6027\u306b\u3064\u3044\u3066\u304a\u4f1d\u3048\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u4eca\u56de\u306f\u3001<strong>\u65b0\u305f\u306b\u767b\u5834\u3057\u305f\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u6cbb\u7642\u85ac\u300c\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\uff08\u30d9\u30e0\u30da\u30c9\u9178\uff09\u300d\u306b\u3064\u3044\u3066\u3054\u7d39\u4ecb\u3057\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306f\u3001\u5fc3\u7b4b\u6897\u585e\u3084\u8133\u6897\u585e\u3068\u3044\u3063\u305f\u52d5\u8108\u786c\u5316\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u4ee3\u8868\u7684\u306a\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u3072\u3068\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3067\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u3084\u30a8\u30bc\u30c1\u30df\u30d6\u306a\u3069\u306e\u5f93\u6765\u85ac\u3060\u3051\u3067\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u5341\u5206\u306b\u4f4e\u4e0b\u3055\u305b\u3089\u308c\u306a\u3044\u5834\u5408\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u7d50\u679c\u3001\u52d5\u8108\u786c\u5316\u304c\u9032\u884c\u3057\u3001\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3092\u767a\u75c7\u3057\u3066\u3057\u307e\u3046\u30b1\u30fc\u30b9\u3082\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3046\u3057\u305f\u72b6\u6cc1\u306e\u4e2d\u3067\u30012025\u5e749\u670819\u65e5\u306b\u65e5\u672c\u3067\u65b0\u305f\u306b\u88fd\u9020\u8ca9\u58f2\u627f\u8a8d\u3092\u53d7\u3051\u305f\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u3001\u5f93\u6765\u306e\u6cbb\u7642\u3067\u5341\u5206\u306a\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u65b9\u306b\u5bfe\u3057\u3001\u65b0\u305f\u306a\u6cbb\u7642\u306e\u9078\u629e\u80a2\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306a\u3069\u3067\u306f\u3001\u3053\u308c\u307e\u3067\u9ad8\u4fa1\u306a\u6ce8\u5c04\u88fd\u5264\uff08\u4f8b\uff1a\u30ec\u30d1\u30fc\u30b5\uff09\u3092\u4f7f\u7528\u3057\u3066\u3044\u305f\u30b1\u30fc\u30b9\u3067\u3082\u3001\u5185\u670d\u85ac\u3067\u5bfe\u5fdc\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u5e83\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u306e\u30d6\u30ed\u30b0\u3067\u306f\u3001\u3053\u306e\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/622323-800x566.jpg\" alt=\"\" class=\"wp-image-625\" style=\"width:414px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/622323-800x566.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/622323-400x283.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/622323.jpg 1600w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u3068\u306f\u3069\u3093\u306a\u85ac\u304b<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u3001ATP\u30af\u30a8\u30f3\u9178\u30ea\u30a2\u30fc\u30bc\u3068\u3044\u3046\u9175\u7d20\u3092\u6291\u3048\u308b\u65b0\u3057\u3044\u30bf\u30a4\u30d7\u306e\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u6cbb\u7642\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f93\u6765\u85ac\u3067\u3042\u308b\u30b9\u30bf\u30c1\u30f3\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5408\u6210\u7d4c\u8def\u306e\u4e0b\u6d41\u3092\u963b\u5bb3\u3057\u307e\u3059\u304c\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u3088\u308a\u4e0a\u6d41\u306e\u6bb5\u968e\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u809d\u81d3\u3067\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5408\u6210\u3092\u3055\u3089\u306b\u52b9\u679c\u7684\u306b\u6291\u5236\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u809d\u81d3\u3067\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5408\u6210\u304c\u6291\u3048\u3089\u308c\u308b\u3068\u3001\u8840\u6db2\u4e2d\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u53d6\u308a\u8fbc\u3080LDL\u53d7\u5bb9\u4f53\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u8840\u4e2d\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08\u4fd7\u306b\u300c\u60aa\u7389\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u300d\u3068\u547c\u3070\u308c\u308b\u3082\u306e\uff09\u304c\u4f4e\u4e0b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3082\u3046\u4e00\u3064\u306e\u5927\u304d\u306a\u7279\u5fb4\u306f\u3001\u809d\u81d3\u3067\u306f\u6d3b\u6027\u5316\u3055\u308c\u308b\u304c\u3001\u7b4b\u8089\u3067\u306f\u307b\u3068\u3093\u3069\u6d3b\u6027\u5316\u3055\u308c\u306a\u3044\u70b9\u3067\u3059\u3002\u30b9\u30bf\u30c1\u30f3\u3067\u3088\u304f\u898b\u3089\u308c\u308b\u7b4b\u8089\u75db\u3084\u5026\u6020\u611f\u3068\u3044\u3063\u305f\u526f\u4f5c\u7528\u306f\u3001\u7b4b\u8089\u3067\u306e\u85ac\u306e\u4f5c\u7528\u306b\u3088\u3063\u3066\u8d77\u3053\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u7b4b\u8089\u306b\u307b\u3068\u3093\u3069\u4f5c\u7528\u3057\u306a\u3044\u305f\u3081\u3001\u30b9\u30bf\u30c1\u30f3\u3067\u7b4b\u8089\u75c7\u72b6\u304c\u51fa\u3084\u3059\u3044\u65b9\u306b\u3082\u4f7f\u7528\u3057\u3084\u3059\u3044\u85ac\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u81e8\u5e8a\u8a66\u9a13\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u52b9\u679c<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e16\u754c\u7684\u306b\u6a29\u5a01\u306e\u3042\u308b\u533b\u5b66\u96d1\u8a8c\u300cThe New England Journal of Medicine\uff08NEJM\uff09\u300d\u306b\u63b2\u8f09\u3055\u308c\u305f CLEAR Harmony\u8a66\u9a13\u3067\u306f\u3001<strong>\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u3092\u6295\u4e0e\u3057\u305f\u7d50\u679c\u300112\u9031\u9593\u5f8c\u306b LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u5e73\u574716.5\uff05\u4f4e\u4e0b \u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f<\/strong>\u3002(<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1803917\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1803917<\/a>)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"570\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa1803917_f1-800x570.jpg\" alt=\"\" class=\"wp-image-620\" style=\"width:494px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa1803917_f1-800x570.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa1803917_f1-400x285.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa1803917_f1.jpg 1271w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right wp-block-paragraph\">(\u51fa\u5178\uff1aN Engl J Med 2019; 380: 1022-1032)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u30b9\u30bf\u30c1\u30f3\u306e\u526f\u4f5c\u7528\u306b\u3088\u308a\u5185\u670d\u304c\u56f0\u96e3\u306a\u60a3\u8005\u3055\u3093\u3092\u5bfe\u8c61\u3068\u3057\u305f CLEAR Serenity\u8a66\u9a13\u3067\u306f\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306b\u3088\u3063\u3066 LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u5e73\u574721.4\uff05\u4f4e\u4e0b\u3057\u3001\u526f\u4f5c\u7528\u306e\u767a\u73fe\u3082\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6509724\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6509724<\/a>)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"705\" height=\"344\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/JAH3-8-e011662-g004.jpg\" alt=\"\" class=\"wp-image-621\" style=\"width:436px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/JAH3-8-e011662-g004.jpg 705w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/JAH3-8-e011662-g004-400x195.jpg 400w\" sizes=\"auto, (max-width: 705px) 100vw, 705px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right wp-block-paragraph\">(\u51fa\u5178\uff1aJ Am Heart Assoc 2019; 2: 8(7) : e011662)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u30012023\u5e74\u306b\u540c\u3058\u304f\u300cNEJM\u300d\u306b\u767a\u8868\u3055\u308c\u305fCLEAR Outcomes\u8a66\u9a13\u3067\u306f\u3001\u7d0414,000\u4eba\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306e\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u6291\u5236\u52b9\u679c\u304c\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u7d50\u679c\u3001<strong>\u4e3b\u8981\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08\u5fc3\u7b4b\u6897\u585e\u3084\u8133\u5352\u4e2d\u306a\u3069\uff09\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u7d0413\uff05\u4f4e\u4e0b\u3059\u308b<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2215024\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2215024<\/a>)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"488\" src=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa2215024_f2-800x488.jpg\" alt=\"\" class=\"wp-image-622\" style=\"width:460px;height:auto\" srcset=\"https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa2215024_f2-800x488.jpg 800w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa2215024_f2-400x244.jpg 400w, https:\/\/nakano-dm.clinic\/blog\/wp-content\/uploads\/2025\/10\/nejmoa2215024_f2.jpg 820w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right wp-block-paragraph\">(\u51fa\u5178\uff1aN Engl J Med 2023; 388: 1353-1364) <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u5358\u306bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e88\u9632\u306b\u3082\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u85ac\u5264 \u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3078\u306e\u671f\u5f85<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306f\u3001\u907a\u4f1d\u7684\u306bLDL\u53d7\u5bb9\u4f53\u306e\u6a5f\u80fd\u306b\u7570\u5e38\u304c\u3042\u308b\u3053\u3068\u306b\u3088\u308a\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u8457\u3057\u304f\u9ad8\u304f\u306a\u308a\u3001\u82e5\u5e74\u671f\u304b\u3089\u72ed\u5fc3\u75c7\u3084\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u5927\u7528\u91cf\u306e\u30b9\u30bf\u30c1\u30f3\u306b\u30a8\u30bc\u30c1\u30df\u30d6\u3092\u4f75\u7528\u3057\u3066\u3082\u5341\u5206\u306bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u3089\u308c\u306a\u3044\u3053\u3068\u304c\u591a\u304f\u3001\u305d\u306e\u3088\u3046\u306a\u5834\u5408\u306b\u306f\u3001\u9ad8\u4fa1\u306a\u6ce8\u5c04\u85ac\u3067\u3042\u308bPCSK9\u963b\u5bb3\u85ac\uff08\u30ec\u30d1\u30fc\u30b5\u306a\u3069\uff09\u304c\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u30b9\u30bf\u30c1\u30f3\u3068\u306f\u7570\u306a\u308b\u4f5c\u7528\u6a5f\u5e8f\u3092\u6301\u3064\u305f\u3081\u3001\u30b9\u30bf\u30c1\u30f3\u3084\u4ed6\u306e\u85ac\u5264\u3068\u306e\u4f75\u7528\u306b\u3088\u308a\u3055\u3089\u306a\u308bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\u304c\u671f\u5f85\u3067\u304d\u308b\u85ac\u5264\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6d77\u5916\u3067\u306f\u3001\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306e\u60a3\u8005\u3055\u3093\u3092\u5bfe\u8c61\u306b\u3057\u305f\u81e8\u5e8a\u8a66\u9a13\u3082\u884c\u308f\u308c\u3066\u304a\u308a\u3001\u65e2\u5b58\u306e\u6cbb\u7642\u3067\u76ee\u6a19\u5024\u306b\u9054\u3057\u306a\u304b\u3063\u305f\u60a3\u8005\u3055\u3093\u306b\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u3092\u8ffd\u52a0\u3057\u305f\u3068\u3053\u308d\u3001<strong>12\u9031\u5f8c\u306b\u7d0431.9\uff05\u306e\u60a3\u8005\u304cLDL-C 100 mg\/dL\u672a\u6e80\u3092\u9054\u6210\u3057\u305f<\/strong>\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38341323\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/38341323<\/a>)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306b\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3092\u542b\u3080\u96e3\u6cbb\u6027\u306e\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306b\u5bfe\u3057\u3066\u3001\u65e2\u5b58\u6cbb\u7642\u3092\u88dc\u3046\u65b0\u305f\u306a\u9078\u629e\u80a2 \u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u5f8c\u3001\u65e5\u672c\u56fd\u5185\u3067\u306e\u4f7f\u7528\u7d4c\u9a13\u306e\u84c4\u7a4d\u306b\u3088\u308a\u3001\u3069\u306e\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u306b\u6700\u3082\u6709\u52b9\u3067\u3042\u308b\u304b\u304c\u3055\u3089\u306b\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u304f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u526f\u4f5c\u7528\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u6bd4\u8f03\u7684\u5b89\u5168\u6027\u306e\u9ad8\u3044\u85ac\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u526f\u4f5c\u7528\u304c\u5168\u304f\u306a\u3044\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>5\uff05\u4ee5\u4e0a\u306e\u5831\u544a\u304c\u3042\u308b\u9ad8\u5c3f\u9178\u8840\u75c7\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981<\/strong>\u3067\u3001\u5c3f\u9178\u5024\u306e\u4e0a\u6607\u306b\u3088\u308a\u75db\u98a8\u767a\u4f5c\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u6bd4\u8f03\u7684\u307e\u308c\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u809d\u6a5f\u80fd\u969c\u5bb3\u3084\u814e\u6a5f\u80fd\u969c\u5bb3\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u3092\u5185\u670d\u3059\u308b\u5834\u5408\u306f\u3001\u8102\u8cea\u306e\u5909\u5316\u3060\u3051\u3067\u306a\u304f\u5c3f\u9178\u5024\u306a\u3069\u306b\u3064\u3044\u3066\u3082\u6ce8\u610f\u6df1\u304f\u7d4c\u904e\u3092\u307f\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u4eca\u5f8c\u306e\u5c55\u671b\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cd\u30af\u30bb\u30c8\u30fc\u30eb\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u304c\u4f7f\u7528\u3067\u304d\u306a\u3044\u60a3\u8005\u3055\u3093\u3084\u3001\u30b9\u30bf\u30c1\u30f3\u3084\u30a8\u30bc\u30c1\u30df\u30d6\u3092\u4f75\u7528\u3057\u3066\u3082\u76ee\u6a19\u5024\u306b\u9054\u3057\u306a\u3044\u60a3\u8005\u3055\u3093\u306b\u3068\u3063\u3066\u3001\u65b0\u305f\u306a\u5e0c\u671b\u3068\u306a\u308b\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b4b\u8089\u3078\u306e\u526f\u4f5c\u7528\u304c\u5c11\u306a\u304f\u3001\u7d4c\u53e3\u85ac\u3068\u3057\u3066\u670d\u7528\u3057\u3084\u3059\u3044\u70b9\u3082\u5927\u304d\u306a\u5229\u70b9\u3067\u3059\u3002\u4e00\u65b9\u3067\u3001\u65b0\u85ac\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u9577\u671f\u7684\u306a\u5b89\u5168\u6027\u3084\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u6291\u5236\u52b9\u679c\u306e\u8a55\u4fa1\u306b\u306f\u3001\u4eca\u5f8c\u306e\u30c7\u30fc\u30bf\u306e\u84c4\u7a4d\u304c\u5fc5\u8981\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u8102\u8cea\u7570\u5e38\u75c7\u306e\u6cbb\u7642\u306f\u85ac\u3060\u3051\u306b\u983c\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u98df\u4e8b\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u898b\u76f4\u3057\u3068\u4e26\u884c\u3057\u3066\u884c\u3046\u3053\u3068\u304c\u4f55\u3088\u308a\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u85ac\u306b\u3088\u308bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\u306f\u3042\u304f\u307e\u3067\u52d5\u8108\u786c\u5316\u3092\u9632\u3050\u305f\u3081\u306e\u4e00\u624b\u6bb5\u3067\u3042\u308a\u3001\u65e5\u3005\u306e\u98df\u4e8b\u7ba1\u7406\u30fb\u4f53\u91cd\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u30fb\u9069\u5ea6\u306a\u904b\u52d5\u306e\u7d99\u7d9a\u3053\u305d\u304c\u3001\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3059\u6700\u3082\u78ba\u304b\u306a\u6cbb\u7642\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p 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